Anticoagulation Meds 💉
Reference guide for anticoagulation medications. LMWH dosing calculators, drug table, and prescribing for anticoagulation and antiplatelet therapy.
💉 LMWH dosing calculators
- Weight-based dosing for enoxaparin (Clexane) and tinzaparin (Innohep) — use the dedicated calculators below.
💊 Anticoagulants & Antiplatelets
- Includes common medications used for anticoagulation and antiplatelet therapy in hospital settings.
- Refer to renal and hepatic considerations when prescribing.
Anticoagulation Medications
Reference table for anticoagulation therapy
| Drug | Dose | Frequency | Route | Notes |
|---|---|---|---|---|
| Enoxaparin (Clexane) | 20-40mg | OD | SC | 40mg OD standard dose. 40mg BD if BMI >40 or >120kg. 20mg for low risk or GFR <30. |
| Tinzaparin (Innohep) | 3500-4500iu | OD | SC | VTE prophylaxis <100kg. |
| Aspirin | 75-300mg | OD | PO | 75mg stent protection. 300mg for MI/CVA. |
| Clopidogrel (Plavix) | 75-600mg | OD | PO | |
| Prasugrel (Efient) | 5-60mg | OD | PO | PCI: 60mg load, 10mg maintenance. 5mg if <60kg. Avoid if prior TIA/stroke. |
| Rivaroxaban (Xarelto) | 20mg | OD | PO | GFR 30-49: 15mg. GFR <30: do not use. |
| Edoxaban (Lixiana) | 60mg | OD | PO | Cr 15-50 OR <60kg OR inhibitors: 30mg. |
| Apixaban (Eliquis) | 2.5-5mg | BD | PO | Use 2.5mg BD if two of: Creat >133, Age >80, Weight <60kg. GFR 15-30: 2.5mg BD. |
Enoxaparin (Clexane)
SCDose:20-40mg
Frequency:OD
Notes: 40mg OD standard dose. 40mg BD if BMI >40 or >120kg. 20mg for low risk or GFR <30.
Tinzaparin (Innohep)
SCDose:3500-4500iu
Frequency:OD
Notes: VTE prophylaxis <100kg.
Aspirin
PODose:75-300mg
Frequency:OD
Notes: 75mg stent protection. 300mg for MI/CVA.
Clopidogrel (Plavix)
PODose:75-600mg
Frequency:OD
Prasugrel (Efient)
PODose:5-60mg
Frequency:OD
Notes: PCI: 60mg load, 10mg maintenance. 5mg if <60kg. Avoid if prior TIA/stroke.
Rivaroxaban (Xarelto)
PODose:20mg
Frequency:OD
Notes: GFR 30-49: 15mg. GFR <30: do not use.
Edoxaban (Lixiana)
PODose:60mg
Frequency:OD
Notes: Cr 15-50 OR <60kg OR inhibitors: 30mg.
Apixaban (Eliquis)
PODose:2.5-5mg
Frequency:BD
Notes: Use 2.5mg BD if two of: Creat >133, Age >80, Weight <60kg. GFR 15-30: 2.5mg BD.
Educational reference only. Medical disclaimer